In the high-level safety laboratory of the National Microorganism Laboratory, a staff member Goto (Shinji Hiwatari) was murdered and deadly virus was stolen. There are laboratories categorized from level 1 to 4 and at level 4, the most dangerous microorganisms such as smallpox and Ebola was stocked. The deadly virus that was stolen by the criminal so powerful and we have no cure one we are infected. Tokyo is facing the unprecedented danger and the special investigation headquarter is set in the metropolitan police department.